- Lipoid pneumonia is an uncommon disease
- caused by the presence of lipid in the alveoli.
- Two types
- exogenous (exogenous lipoid pneumonia) or
- inhaled nose drops with an oil base, or
- accidental inhalation of cosmetic oil.
- Amiodarone is an anti-arrythmic known to cause this condition.
- Fire breather’s pneumonia
- from the inhalation of hydrocarbon fuel
- Gastroesophageal reflux.
- endogenous/idiopathic (endogenous lipoid pneumonia)
- obstructed airway is, it is often the case that
- lipid-laden macrophages and giant cells fill the lumen
- distal to the obstruction,
- of the disconnected airspace.
- exogenous (exogenous lipoid pneumonia) or
- Two types
- Resulting in
- Clinicically
- insidious onset
- dyspnea and/or cough.
- insidious onset
- Imaging
- consolidations,
- ground-glass attenuation,
- airspace nodules and
- ‘crazy-paving’ pattern. However, the radiological
- Pathologically,
- lipid-laden macrophages.
-
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Lipid laden macrophages in a patient with lipoid pneumonia
Courtesy pathologyoutlines.com/
- Lab
- Lipid-laden macrophages in respiratory samples from
- sputum,
- bronchoalveolar lavage fluid or
- fine-needle aspiration cytology/biopsy from lung lesions.
- Lipid-laden macrophages in respiratory samples from
- Treatment protocols for this illness are
- poorly defined.
- Clinicically
A second Patient with achalasia and chronic aspiration
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Lipoid Pneumonia78 year old female with achalasia and likely chronic aspiration
Note the distended esaophagus with air fluid level
Ashley Davidoff MD TheCommonVein.net