• 50 year old female with
    • Alpha-1 antitrypsin deficiency (AATD) r
      • severe deficiency occurring in Z allele homozygotes (PiZZ), 
    • early-onset emphysema.
    • former smoker 35 pack year

CXR Lower Lobe Emphysema 

CXR  Alpha-1 antitrypsin deficiency with Panlobular Emphysema
CXR shows hyperinflation with basilar prominence consistent with panlobular emphysema secondary to Alpha-1 antitrypsin deficiency
Ashley Davidoff TheCommonVein.net
CXR  Alpha-1 antitrypsin deficiency with Panlobular Emphysema
CXR shows hyperinflation with basilar prominence consistent with panlobular emphysema secondary to Alpha-1 antitrypsin deficiency
Ashley Davidoff TheCommonVein.net

 

CT Upper Lobe Centrilobular  Emphysema and Bronchitis

CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema
Scout for CT scan shows hyperinflation with basilar prominence consistent with panlobular emphysema secondary to Alpha-1 antitrypsin deficiency
Ashley Davidoff TheCommonVein.net
CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema
Axial  CT scan shows mild centrilobular emphysema in the upper lobes Patient has a 36pack year smoking history
Ashley Davidoff TheCommonVein.net

 

CT Lobe Centrilobular and Lower Lobe Panlobular Emphysema and Bronchitis

CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema.
Axial  CT scan shows lower lobe panlobular emphysema and bronchitis
Ashley Davidoff TheCommonVein.net
CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema.
Axial  CT scan shows lower lobe panlobular emphysema and bronchitis
Ashley Davidoff TheCommonVein.net
CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema.
Axial  CT scan shows lower lobe panlobular emphysema and bronchitis
Ashley Davidoff TheCommonVein.net
CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema.
Axial  CT scan shows lower lobe panlobular emphysema and bronchitis
Ashley Davidoff TheCommonVein.net
CT   Alpha-1 antitrypsin deficiency with Panlobular Emphysema.
Axial  CT scan shows lower lobe panlobular emphysema and bronchitis
Ashley Davidoff TheCommonVein.net