Overview of the Anatomy of the Lungs Large Airways and Small Airways Ashley Davidoff MD TheCommonVein.net lungs-0740nL
Overview of the Histology of the Lungs from the Trachea to the Alveolus Ashley Davidoff MD TheCommonVein.net lungs-0742n
Histology of the terminal and respiratory bronchiole showing the cellular components of the mucosa including the ciliated cuboidal cells, cells, Clara cell and the neuroendocrine cells Ashley Davidoff MD TheCommonVein.net lungs-0742 -lo resb
Histology of the respiratory bronchiole showing the cellular components of the mucosa including the ciliated cuboidal cells, cells, Clara cell and the neuroendocrine cells Ashley Davidoff MD TheCommonVein.net lungs-0747
Histology of the terminal bronchiole showing the cellular components of the mucosa including the ciliated columnar cells, Clara cell and the neuroendocrine cells Ashley Davidoff MD TheCommonVein.net lungs-0746
Cells of the Bronchioles Ashley Davidoff MD TheCommonVein.net lungs-0741
Cells of the Bronchioles Ashley Davidoff MD TheCommonVein.net lungs-0741n
Histology of the Large and Medium Sized Airways Airways are lined by a pseudostratified ciliated columnar epithelium interspersed with mucus secreting goblet cells Ashley Davidoff TheCommonVein.net lungs-00674b01-lo res
As the medium sized airways progress to to the small airways they lose many of the goblet cells, become a simple epithelium and remain ciliated Ashley Davidoff TheCommonVein.net lungs-00675-lo-res
As the terminal bronchial transitions to the respiratory bronchial the mucosa becomes non ciliated and cuboidal Ashley Davidoff TheCommonVein.net lungs-00676
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At the level of the mebranous airways (respiratory bronchiole, alveolar duct, alveolar sac and alveoli, the mucosa becomes mostly a simple squamous epithelium
Ashley Davidoff
TheCommonVein.net lungs-00677
Cells
Club Cell Ashley Davidoff MD TheCommonVein.net lungs-0743
The Alveolus Ashley Davidoff TheCommonVein.net lungs-00679
Cellular Makeup of the Normal Alveolus Ashley Davidoff TheCommonVein.net lungs-0689
Macrophage Ashley Davidoff MD The4CommonVein.net cells-0072
Smokers Macrophage Ashley Davidoff TheCommonVein.net lungs-00686
Alveolar Macrophages Ashley Davidoff TheCommonVein.net lungs-0063
Simple cuboidal cell with reddish foamy and sometimes vacuolated cytoplasm Ashley Davidoff TheCommonVein.net lungs-0062
Simple squamous epithelium with pale staining cytoplasm Ashley Davidoff TheCommonVein.net lungs-0061
Diseases
Membranous airways (respiratory bronchiole, alveolar ducts, alveolar sacs) Ashley Davidoff TheCommonVein.net lungs-00685
Pathophysiology of Cigarette Smoking on Medium Sized Airways Ashley Davidoff TheCommonVein.net lungs-00684
Pathophysiology of Cigarette Smoking on Medium Sized Airways, Small Airways and Alveoli Ashley Davidoff TheCommonVein.net lungs-00683
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Smoking and the Alveolus –
Ashley Davidoff TheCommonVein.net lungs-00687
ARDS ? Causes The lung is injured either by direst causes most commonly pneumonia, aspiration or from inhalation of toxic substances. Severe systemic illnesses, most commonly sepsis with shock, and severe trauma are considered indirect causes. Ashley Davidoff TheCommonVein.net lungs-0690
Early Events in the Pathophysiology of the ARDS The initial injury results in an acute severe inflammatory response consisting hyperemia , edema with migration initially of neutrophils in the first 6-24 hours followed by monocytes (24-48hours). The intra -alveolar macrophages are activated. Ashley Davidoff TheCommonVein.net lungs-0691
Result of Cellular Response The cells of the immune system release cytokines, chemotactic agents and proteases. Immune cells , macrophages and fibroblasts are attracted to the interstitium. Some of proinflammatory agents are toxic to the cell lining causing damage to the surfactant, type 1 pneumocytes and the capillary endothelium. There is progressive edema. Ashley Davidoff TheCommonVein.net lungs-0692
Hyaline Membrane A hyaline membrane evolves covering the damaged surface of the alveolus. This impedes gas exchange Ashley Davidoff TheCommonVein.net lungs-0694
Chronic Inflammation ? The Basics Ashley Davidoff MD TheCommonVein.net Chronic Inflammation ? The Basics Ashley Davidoff MD TheCommonVein.net lungs-0699d
Basic Structure of Tubular Systems key words art mucosa submucosa muscularis adventitia serosa histology tube colon small bowel lung bronchus bronchi esophagus stomach large bowel bile duct ureter tube principles Ashley Davidoff TheCommonVein.net 32347
Mucosal Lesion key words mucosa submucosa muscularis adventitia serosa mucosal mass polyp neoplasm carcinoma acute angles with the lumen histopathology imaging diagnosis Ashley Davidoff TheCommonVein.net 32347d01
Submucosal Lesion key words mucosa submucosa muscularis adventitia serosa submucosal mass edema hemorrhage obtuse angles or right angle 90 degree ninety degree angle with the lumen histopathology imaging diagnosis Ashley Davidoff TheCommonVein.net 32347d02
Submucosal Lesion key words mucosa submucosa muscularis adventitia serosa submucosal mass edema hemorrhage obtuse angles or right with the lumen histopathology imaging diagnosis Ashley Davidoff TheCommonVein.net 32347d03
Extrinsic Lesion key words mucosa submucosa muscularis adventitia serosa submucosal mass edema hemorrhage neoplasm malignancy benign obtuse angles with the lumen histopathology imaging diagnosis Ashley Davidoff TheCommonVein.net 32347d04
Circumferential Lesion key words mucosa submucosa muscularis adventitia serosa submucosal mass edema hemorrhage neoplasm malignancy benign obtuse angles with the lumen circumferential narrowing constriction obstruction histopathology imaging diagnosis Ashley Davidoff TheCommonVein.net 32347d06