• 47 year old female
  • Systemic lupus erythematosus 30 years ago
  • Sjogren’s syndrome (20 years ago)
  • Family history
    • Rheumatoid arthritis
    • SLE
    • Kartageners
  • PFT
    • persistence of airflow obstruction
    • borderline restrictive disease
    • mild decrease in diffusion capacity
  • Rx
    • On steroids
  • CT 7 years ago

  • Thin walled Cysts
  • 47f-SLE-Sjogrens-LIP-vs-Birt-Hogg-Dube-basilar-thin-walled-cysts-lymphadenopathy-001-CT-7-years-ago.jpg

    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Ashley Davidoff TheCommonVein.net

    Mild Middle Lobe Reticular Changes

    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

    Calcification associated with Cyst in the Lower Lobe

    Calcification associated with Cyst
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

    Subsegmental infiltrate around the Bronchovascular bundles in the Right Lower Lobe 7 years ago

    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Lymphadenopathy 7 years ago
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

    47f-SLE-Sjogrens-LIP-vs-Birt-Hogg-Dube-basilar-thin-walled-cysts-lymphadenopathy-004-CT-7-years-ago.jpg

    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

     

    1 Year Ago

  • Cysts Mild Progression 
  • 47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

  • Lymphadenopathy Improved
  • Improved right paratracheal Lymphadenopathy
    47f SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy CT 1year ago
    Ashley Davidoff TheCommonVein.net

  • Improved RLL Infiltrate
  • 47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Right Lower Lobe Infiltrate
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Right Lower Lobe Infiltrate
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

    Progressive Lingular Reticular Changes and Perhaps Tree in Bud?

     

  • Progressive Lingular Reticular Changes and Perhaps Tree in Bud?
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Ashley Davidoff TheCommonVein.net

    Stable Calcification and a Cyst

  • Stable Calcification and a Cyst
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Ashley Davidoff TheCommonVein.net

  •  Current

  • Cystic Changes Stable
  • Stable Cystic Changes
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Cysts Associated with Blood Vessels
  • Cysts Associated with Blood Vessels in RLL
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

  • Persistent Decreased Adenopathy ? Early Calcification
  • Persistent Decrease in Adenopathy
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

    Persistent Decrease in Adenopathy
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

  • RLL Infiltrate Progressive Peribronchial Changes
  • Progressive RLL Infiltrate with Peribronchial Changes
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

    47f-SLE-Sjogrens-LIP-vs-Birt-Hogg-Dube-basilar-thin-walled-cysts-lymphadenopathy-020-CT-current.jpg

    Progressive RLL Infiltrate with Peribronchial Changes
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Progressive RLL Infiltrate with Peribronchial Changes
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Progressive RLL Infiltrate with Thickened Interlobular Septa
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net
    Lingular Changes of Nodules and Mild Reticular Change ? Improved
  • Lingular Changes of Nodules and Mild Reticular Change ? Improved
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff TheCommonVein.net

  • Stable Calcification and a Cyst
  • Stable Calcification in a Cyst ? Amyloid 47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy Subsegmental right lower lobe infiltrate Ashley Davidoff

    Stable Calcification in a Cyst ? Amyloid
    47 F SLE Sjogrens LIP vs Birt-Hogg-Dube basilar thin walled cysts lymphadenopathy
    Subsegmental right lower lobe infiltrate
    Ashley Davidoff

  • CT multiple large
    • cysts bilaterally, with
    • lower lobe predominance,
      • up to 4.1 cm
      • slightly dysmorphic in shape,
      • some simple and
      • some multiseptated,
      • not significantly changed since 4 years prior , but progressed over 7 yearsDifferential Diagnosis
        • Birt-Hogg-Dube syndrome.
        • Atypical LIP (lymphocytic interstitial pneumonitis) In the context of a
          known negative FCLN gene mutation and an established diagnosis of
          Sjogren’s syndrome, this could represent an atypical presentation of
          lymphocytic interstitial pneumonitis.