Uncategorized Acute Phase Early Events in the Pathophysiology of the ARDSThe initial injury results in an acute severe inflammatory response consisting hyperemia , edema with migration initially of neutrophils in the first 6-24 hours followed by monocytes (24-48hours). The intra -alveolar macrophages are activated.Ashley DavidoffTheCommonVein.net lungs-0691 Diffuse or Patchy Ground Glass Changes – ARDS 43FDiffuse Ground Glass PatternAshley Davidoff TheCommonVein.net 117653 ARDS from Sepsis 79MPatchy Diffuse Ground Glass PatternDominant – Central LocationRelative Lower Lobes and Subpleural SparingAshley Davidoff TheCommonVein.net 134304 ARDS from sepsis 79MPatchy Diffuse Ground Glass Pattern and right pleural effusionAshley Davidoff TheCommonVein.net 134300 ARDS5ARDS54 year old female with sepsis and acute respiratory distress syndrome. Coronal CT shows diffuse ground glass changes with subsegmental regions of consolidation. The posterior aspect of the lungs showed consolidation characteristic of the antero-posterior density gradient of ARDS Ashley Davidoff TheCommonVein.net 54-f002 ARDS Ground Glass with Subpleural Sparing ARDS from Sepsis 79MPatchy Diffuse Ground Glass Pattern, thickened interlobular septa Subpleural SparingAshley Davidoff TheCommonVein.net 134294 Diffuse Ground Glass Changes and Subpleural SparingARDS Sickle Cell CrisisThe CXR in this 26 year old male in sickle cell crisis shows diffuse and symmetrical ground glass changes with subpleural sparingAshley Davidoff TheCommonVein.net b11662-02 Anteroposterior Density Gradient ARDS -Anteroposterior Density GradientSince the patient is mostly in a supine position in the ICU setting the disease is distributed based on gravitational forces with the more dense consolidation in the most dependent regions posteriorly and less dense with ground glass changes anteriorly. Anteriorly more normal or even hyperexpanded lung is present.Ashley Davidoff TheCommonVein.net lungs-0786 ARDS -Anteroposterior Density GradientA Memory Image for ARDSThe anterior aspect of a CT in axial projection shows AeRation and the posterior aspect shows increase DenSity due to the gravitational effect of the fluid in the lungsAshley Davidoff TheCommonVein.net lungs-0786-01L ARDS54 year old female with sepsis and acute respiratory distress syndrome . Axial CT at the level of the carina shows ground glass changes and bilateral posterior consolidation reminiscent of an antero-posterior density gradient – a characteristic radiological finding of ARDS Ashley Davidoff TheCommonVein.net 54-f003-ARDS 53F ARDSDiffuse Ground Glass Pattern and A-P gradientAshley Davidoff TheCommonVein.net 134245 Subacute and Chronic Phases Traction Bronchiectasis 53F ARDS 8 months laterDiffuse Ground Glass Pattern with Mild Traction BronchiectasisAshley Davidoff TheCommonVein.net 134262