A cavity in the lungs is an air-filled space within an area of lung
tissue that has undergone necrosis, typically surrounded by a
thickened wall. Cavities can result from infections (such as
tuberculosis, fungal infections, or bacterial abscesses),
malignancies, and certain autoimmune diseases like
granulomatosis with polyangiitis. The pathogenesis involves tissue
destruction, usually due to infection or inflammation, which leads
to localized death of lung tissue, creating an empty space. Cavities
can lead to symptoms such as chronic cough, fever, and, if
infected, production of purulent sputum or hemoptysis. Diagnosis is
primarily based on imaging, with chest X-rays or CT scans showing
an air-filled space with a thickened wall, and further confirmed
through microbiological cultures or biopsy if malignancy or specific
infections are suspected (Etesami)
LUNG ABSCESS LIP HIV AIDS and LYMPHOMA 27 year old male with a history of perinatal HIV with intermittent highly active antiretroviral therapy (HAART) compliance with a CD4 count of < 50 with biopsy confirmed B cell lymphoma of the liver, s/p CHOP therapy , chronic esophageal strictures s/p dilatations, esophageal candidiasis, LIP, bronchiectasis pancreatitis, and portal vein and splenic vein thrombosis. Initial Chest X-ray shows a diffuse reticular pattern with cystic changes dominant at the bases. CT at that time confirmed the presence of diffuse cystic changes with the largest cysts at the lung bases. Ascites and splenomegaly are also present He presented one month later with fever and neutropenia. CT showed an abscess cavity in the right upper lobe in the right upper lobe, thickened distal esophagus with edematous wall, atrophic gastritis and ascites. Bronchovascular thickening along a bronchiectatic segment in the right upper lobe was present in the last CT Ashley Davidoff MD TheCommonVein.net 017Lu 132031