• The azygoesophageal line is an
    • anatomical landmark representing
      the interface between the azygos vein and the esophagus,
    • typically located at the T5 to T6 vertebral levels.
    • It serves as a
      • critical
        reference point when assessing the posterior mediastinum and
      • identifying surrounding structures.
    • The azygos vein, which runs
      along the right side of the thoracic spine
      • drains blood from the thoracic wall and upper lumbar regions into the superior vena cava, while
    • the esophagus lies
      • anterior to the aorta and posterior to the
        trachea.
      1. Chest X-Ray (CXR):
        • Appears as a thin vertical line on the right side of the mediastinum, extending downward from the azygos arch to the diaphragm.
        • Normal Appearance:
          • Smooth and curvilinear.
        • Abnormalities:
          • Deviation, widening, or irregularity suggests pathological processes affecting the mediastinum, esophagus, or adjacent lung.
      2. CT Imaging:
        • Clearly visualizes the structures forming the line, including:
          • The azygos vein, esophagus, and mediastinal fat.
          • The interface between the right lung and mediastinal structures.
        • Normal Line:
          • A sharp, well-defined interface on axial cuts.
        • Abnormal Line:
          • Bowing, irregularity, or distortion due to mass effect, esophageal dilation, or other pathologies.

    • Common Causes of Abnormalities

      1. Esophageal Disorders:
        • Esophageal Dilation:
          • Achalasia, esophageal carcinoma, or strictures can displace or distort the azygo-esophageal line.
        • Hiatal Hernia:
          • Can cause a focal bulge in the lower portion of the line.
      2. Mediastinal Masses:
        • Lymphadenopathy:
          • From malignancies (e.g., lymphoma, lung cancer) or infections (e.g., tuberculosis).
        • Mediastinal Tumors:
          • Neurogenic tumors or esophageal tumors can cause deviation or widening.
      3. Azygos Vein Enlargement:
        • Azygos Continuation of the IVC:
          • Congenital anomaly causing a widened azygo-esophageal line.
        • Venous Congestion:
          • Secondary to right heart failure or superior vena cava syndrome.
      4. Pleural Disease:
        • Pleural Effusion:
          • May obscure the lower portion of the azygo-esophageal line.
        • Right Lower Lobe Atelectasis:
          • Causes a shift toward the collapsed lung, narrowing the line.
      5. Other Causes:
        • Vertebral Abnormalities:
          • Scoliosis or kyphosis can distort the line.
        • Subcarinal Pathology:
          • Enlarged lymph nodes or masses in the subcarinal region.

      Clinical Relevance

      The azygo-esophageal line is a subtle but important feature in chest imaging. Changes in its appearance can provide clues to underlying mediastinal or esophageal diseases, prompting further diagnostic workup (e.g., CT, endoscopy).

Azygo-esophageal Line aka Azygo-esophageal Stripe
TheCommonVein.net
Ashley Davidoff MD 32682c
Azygo-esophageal Line aka Azygo-esophageal Stripe
Note the right border of the line is formed by the ascending azygous vein (red arrowheads) and the azygous vein appears as a rounded density above the right main stem bronchus (blue arrowhead) just before it enters the upstream SVC.   A liner collection of air is noted in the  esophagus (pink arrowheads).
TheCommonVein.net  Ashley Davidoff MD 32682cL