- 50 year old female with
- Alpha-1 antitrypsin deficiency (AATD) r
- severe deficiency occurring in Z allele homozygotes (PiZZ),
- early-onset emphysema.
- former smoker 35 pack year
CXR Lower Lobe Emphysema
CT Upper Lobe Centrilobular Emphysema and Bronchitis
CT Lobe Centrilobular and Lower Lobe Panlobular Emphysema and Bronchitis