1827 – 

The earliest photograph available of a building and a tree taken by Frenchman  Joseph Niépce later to become Nicephore Niepce was in 1827 and it took 8 hours for exposure and who knows how long to develop.

Nicéphore Niépce,
Courtesy Wiki

8 hour exposure

The earliest saved photographic image (Heliograph on pewter plate) from 1827 by Joseph Nicéphore Niépce, taken at Le Gras, France.

1895

In 1895 Wilhelm Roentgen discovered the use of X-Rays

Wilhelm Conrad Röntgen
Courtesy Wikipedia

15minutes

First medical X-ray by Wilhelm Röntgen of his wife Anna Bertha Ludwig’s hand in 1895
Courtesy Wikipedia

 

Godfrey N. Hounsfield
1975 Nobel prize
Award Winner –

Although computerized tomography (CT) ? or computerized axial tomography (CAT) ? scan is associated with science and technology, many would be surprised to learn that its humble beginnings were through a company – EMI that was successful in promoting the Beatles

From slideshare.net/kimberleyfinn/emi-case-study
From slideshare.net/kimberleyfinn/emi-case-study

 

The Beatles in 1965; from left to right: John Lennon, Ringo Starr, Paul McCartney and George Harrison.
Their record company was EMI for whom Godfery Hounsfield worked and it was through their success as a record company that they were able to finance the research of Godfrey Hounsfield

could possibly be rooted in rock and roll. Specifically, the creation of this incredible technology has been widely attributed to the success of The Beatles in the 60s.

1972 CT scan

The very first CT scanner prototype. Invented by Hounsfield at EMI. This picture was taken at the UKRC 2005 exhibition in Manchester G-MEX centre. Philipcosson 08:42, 20 July 2006
Wiki
Allan Macleod Cormack
South African American physicist who won the 1979 Nobel Prize in Physiology or Medicine (along with Godfrey Hounsfield) for his work on X-ray computed tomography (CT)
Wiki

Allan Cormack, a physicist, developed a
mathematical process for calculating the distribution of x-ray attenuation values throughout a simulated body section.

The first clinical image was taken by Hounsfield in 1972 on an EMI scanner when he scanned the brain of a cow –  It  took several hours to scan a single slice and several days to produce the image.  The graininess and lack of clarity in both images is similar with poor resolution , due to the long exposure times.

  • 1972 First Clinical Scan

  • 30 minutes for the scan,
    • a drive across town with the magnetic tapes to EMI,
    • 2.5 hours processing the data on an EMI mainframe computer
    • capturing the image with a Polaroid camera
    • racing back to the hospital
  • Result
      • a cystic mass about the size of a plum in the right frontal region
The first clinical CT scan, acquired October 1971 at Atkinson Morley?s Hospital in London

Progress in both the fields of photography and CT scanning have evolved principally due to the speed with which the image is acquired.  The current advances depend  heavily on both the speed  as well as the digital method.  Thus advance, particularly in the world of biology, where things are on the move, have paralleled the progressive sophistication of computers.

1973  Robert Ledley –  a whole-body scanner

Single Row of Detectors 5,7, 10mm

2 Seconds with 6 second interscan delay

The gantry or the doughnut through which the patient is scanned ? originally contained a singe row of detectors and the slice thickness thus depended on the collimation of the beam and the size of the detectors in general 5,7, 10mm

The gantry was able to rotate one way (say clockwise) and then had to reverse direction and rotate  counterclockwise to uncoil the cables that were involved in delivering the high voltage power, and the data.  Each 2-second scan was separated by a 6-second interscan delay (needed to reorient the x-ray source-detector assembly within the gantry to prevent entanglement of the cables)  The patient also needed to be moved to acquire the next slice.  If the patient happened to move, breath or a heart beat occur between the move, then the slices did not line up.  The brain was the most photogenic of them all ? (mirror mirror on the wall ), because it was able to stay still for the camera ? but peristalsis, respiratory motion and heart beats made moving targets in the rest of the body.

Slip Ring Technology late 1970’s

The application of slip ring technology, which enabled a continuous motion of the gantry in helical fashion allowed the advances necessary First slip-ring CT system was introduced by Varian in the 1970s,

1980’s Spiral Scanning 1988

Sieman?s capitalized in 1988 by introducing helical or spiral scanning technology.

1992 Dual Row of Detectors

A second breakthrough was introduced by Elscint who introduced a second row of detectors in 1992, which became 4 in 1998, and now we are up to 256.  Thus we have to in the world of analog photography speed and resolution are major factors With the advent of digital techniques speed and resolution ? now measured in amount of data strength speed and power of the computer

The first computed tomography machine that was commercially available in the United States (about 1972) used an 80 by 80 pixel matrix. A cross-sectional image of the brain

First Clinical CT scan of the Brain
CT scan performed in 2000 wirth intravenous contrast shows a complex cystic mass with an enhancing wall
Ashley Davidoff thecommonvein.net 14917

A similar cross section of the brain done on a more modern 512 by 512 matrix machine (14917 )

Godfrey Newbold Hounsfield, a British scientist, and Allan M. Cormack, a South African physicist, won the Nobel Prize in physiology or medicine in 1979 for their development of computer assisted tomography.

1963
Cormack AM

1972
Hounsfield GN

EMI Mark I
first commercial scanner required 41/2 minutes to complete a
brain scan

first-generation
line integral collected using an
x-ray tube and a
single detector

second-generation scanners
line integral collected using an
x-ray tube and a
multiple detectors

third-generation systems
fan beam x-ray source
large array of detectors

fourth-generation systems
fan beam x-ray source
fixed detector array completely surrounds the patient”

Wiley On Line Library

 

Links and References