44 year old male with Chronic Renal Failure s/p Renal Transplant and Osteodystrophy due to secondary hyperparathyroidism
Scout film of a CT scan shows protrusio deformity in the right hip and a fracture
Brown tumors, also known as osteitis fibrosa cystica, are a rare manifestation of advanced primary or secondary hyperparathyroidism, which can be associated with renal osteodystrophy. They are not true tumors but rather localized, benign, bone lesions resulting from excessive parathyroid hormone (PTH) secretion and the subsequent resorption of bone. Brown tumors can affect various bones in the body, including those in the skull, long bones, ribs, and pelvis. When they occur in the context of renal osteodystrophy, it is often due to chronic kidney disease (CKD) and its associated abnormalities in mineral metabolism.
Looser’s Zones
Looser’s zones, also known as Looser’s lines or pseudofractures, are radiographic findings associated with osteomalacia. Osteomalacia is a condition characterized by the softening and weakening of bones due to a deficiency in vitamin D, calcium, or phosphate. Looser’s zones represent areas of incomplete stress fractures or microfractures in bones and are typically seen on X-rays. These pseudofractures can be mistaken for actual bone fractures, but they are a result of weakened bone rather than acute trauma.