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Indications
- https://heart.thecommonvein.net/95h-normal-calcium-score-normal-coronaries/
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- 41 year old male with significant family history
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Definition
- preventive tool
- used to identify calcific atheroscleosis
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BAckground
- Approximately 50% of all cardiovascular disease (CVD)?related deaths
- no prior cardiac symptoms or diagnoses,
- Approximately 50% of all cardiovascular disease (CVD)?related deaths
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Aim
- Identify the presence of atherosclerosis in
- patients in whom management may change
- ie those wh would benefit for conservative preventive management
- positive family history
- ACC Risk Calculator
- categorised
- low-risk,
- intermediate-risk, and h
- igh-risk for future heart attacks.
- ie those wh would benefit for conservative preventive management
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Indications
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- Smoking,
- Obesity,
- hypercholesterolemia
- hypertension,
- diabetes
- sedentary lifestyl
- positive family history of myocardial infarction,
- inflammatory diseases like rheumatoid arthritis, diabetes.
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Calcium score should be considered in people between 45-70 years of age.
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Under 40, the zero score?s negative predictive value is not high since there has not been enough time for the lipid-rich-plaques to calcify.
- Above 70,
- nearly everyone has calcification of the coronary arteries.
- positive unless significantly elevated,
- not necessarily signify high risk.
- calcium score of 0
- very high negative predictive value.
- positive unless significantly elevated,
- nearly everyone has calcification of the coronary arteries.
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Contraindications
- Relative
- very low pretest probability
- very high CV risk
- since they prevention Rx anyway
- Relative
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Advantages
- High sensitivity for atherosclerosis
- low radiation 1mSV
- the more burden the more benefit with conservative therapy
- statins
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Disadvantages
- Radiation
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Method
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Patient Prep
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Technique
- Gated
- Multi
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Results
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- Report should include
- the absolute Agatston score and the
- age, sex, and race-specific CAC percentile;
- the number of vessels with CAC;
- the presence of CAC in the left main coronary artery;
- specific highlighting of individuals with very high CAC scores of greater than 1000
- Test of plaque burden
- A calcium score of 20 in a
- 70-year-old person is low but in a
- 35-40-year-old is significantly ele
- should be considered considerably elevated.
- Report should include
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Conclusions
- Discussion
- In a patient with negative calcium score – we do not know if there is fibrofatty plaque
- A high coronary calcium score can change someone?s risk from low to high but not the other way. A low or even zero calcium score does not change the status of a high-risk patient to a low-risk. A ?high risk? individual will remain ?high risk? regardless of their calcium score.
- calcium score should always be interpreted in the
- context of other risk factors
- never solely.
- 0 in a low-risk patient is highly reassuring.
- 0 in high risk patient
- smokes
- high cholesterol or
- high blood pressure
- is less predictive.
- Associated diseases with high calcium score
- cancer
- Incidental Finding
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Links and References
- Journal Articles
- Patel, J et al Assessment of Coronary Artery Calcium Scoring to Guide Statin Therapy Allocation According to Risk-Enhancing FactorsThe Multi-Ethnic Study of Atherosclerosis
- Videos
- Blaha Michael Yale Grand Rounds 2022
- Medcape MedPage Peer to Peer Philip Green
- Guidelines
- 2022
- Journal Articles