The isthmus is a slight constriction (approximately 3 mm) of the aorta just proximal to the point of attachment of the ductus arteriosus and distal to the origin of the left subclavian. It is characterized structurally by minimal narrowing of the tubular segment at that point. It serves as a marker for the site of the ductus arteriosus in fetal circulation and for the ligamentum arteriosum, a fibrous remnant in the child and adult. The narrowing of the aorta is simply the remnant of the embryologic structure. Common diseases at this include atherosclerosis, coarctation of the aorta and patent ductus arteriosus. Diagnostic studies include CT imaging, aortography, MRI and echocardiography. Surgical treatment is most common.
PDA is a congenital persistence of an emryolog shunt – cause unknown sometimes in isolation sometimes in association with other congenital lesions results in left to right shuny increased blood flow to lungs relative decrease in flow to body with most clinical manifestations relating to increase fow Left untreated the iolated lesion will usuallyprogress to pulmonary hypertension and eventually Eisenmenger physiology meaning shunt goes right to left with subsequent cyanosis
dx echocardiography rx Non invasive chemical and surgical intervention are all options
Patent Ductus Arteriosus
42326.800 aorta pulmonary artery finding PDA patent ductus arteriosus left to right shunt arteriovenous malformation CTscan Courtesy Ashley Davidoff MD
Coarctatation of the Aorta
Congenital – may be in isolation part of the HLHS or in association with other congenital heart diseases dx imaging echo sometimes MRI rx Non invasive techniques and surgical
Few types – most common is at the level of the istmus
Coartcation of the Aorta
00254c04 This combination of an angiogram and MRI show a focal coarctation of the aorta distal to the dilated left subclavian artery. Note the large internal mammary artery in the angiogram (a) Courtesy Ashley Davidoff MD 00254c02 CVS aorta thorax thoracic aorta coarctation
Aortic Interruption
Congenital – may be in isolation part of the HLHS or in association with other congenital heart diseases dx imaging echo sometimes MRI rx Non invasive techniques and surgical
Aortic Interruption at the Level of the Isthmus
The most obvious finding in this CXR (a) with pleuro-parenchymal changes is not the most significant. In image (b) the highlighted ribs reveal rib notching characteristic of coarctation of the aorta. The lateral examination (c) in this instance is not helpful. In the early phase of the angiogram(d), there appears to be complete interruption of the aorta with a large left subclavian artery acting as a collateral pathway. The sbsequent images e, and f, show progressive filling of the isthmus and distal thoracic aorta. The coarcatation becomes apparent characterised by a “3” sign. 35107c Courtesy Laura Feldman MD code CVS artery aorta thorax coarctation rib notching bone collateral
Aortic Trauma
Few types – most common is at the level of the isthmus
Traumatic Pseudoaneurysm at the Level of the Isthmus
35260 Courtesy of Laura Feldman MD. code aneurysm aorta artery pseudoaneurysm thorax trauma traumatic anerusym
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Aortic Interruption at the Level of the Isthmus
The most obvious finding in this CXR (a) with pleuro-parenchymal changes is not the most significant. In image (b) the highlighted ribs reveal rib notching characteristic of coarctation of the aorta. The lateral examination (c) in this instance is not helpful. In the early phase of the angiogram(d), there appears to be complete interruption of the aorta with a large left subclavian artery acting as a collateral pathway. The sbsequent images e, and f, show progressive filling of the isthmus and distal thoracic aorta. The coarcatation becomes apparent characterised by a “3” sign. 35107c Courtesy Laura Feldman MD code CVS artery aorta thorax coarctation rib notching bone collateral
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Aortic Interruption at the Level of the Isthmus
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00254c04 This combination of an angiogram and MRI show a focal coarctation of the aorta distal to the dilated left subclavian artery. Note the large internal mammary artery in the angiogram (a) Courtesy Ashley Davidoff MD 00254c02 CVS aorta thorax thoracic aorta coarctation
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00254c04 This combination of an angiogram and MRI show a focal coarctation of the aorta distal to the dilated left subclavian artery. Note the large internal mammary artery in the angiogram (a) Courtesy Ashley Davidoff MD 00254c02 CVS aorta thorax thoracic aorta coarctation
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