The adrenal gland is very vascular, receiving an estimated 6 to 7 ml/g per minute, or about 25ml/minute in the resting state. Why does it have such a large blood supply? The body’s second to second need to respond to crisis situations requires enough blood to pass by the adrenals to circulate important and necessary hormones.
The blood supply of the adrenal gland is derived from three adrenal arteries: the superior artery is a branch of the inferior phrenic artery; the middle artery arises directly from the aorta; and the inferior artery arises from the renal artery.
The primary blood supply of the right adrenal comes from the superior and inferior adrenal arteries, whereas the left adrenal is supplied primarily by the middle and inferior adrenal arteries. The three arteries branch, and each gland may have up to 50 small arterial branches enter the perimeter, supplying a gland that obviously commands a tremendous blood supply.
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Anatomy and Physiology of the Adrenal Glands: Arterial Supply – Intra- Adrenal Anatomy
Up to 50 to 60 small feeder vessels penetrate the anterior and posterior surfaces of the glands and form a plexus beneath the capsule. Cortical arteries supply the cortex from the subcapsular plexus, which drains centripetally toward the medulla. Medullary arteries pass through the cortex and supply the medulla directly. In the zona reticularis, the capillaries coalesce to form progressively larger venous sinuses that drain centrally.
Medullary capillaries form venous channels, which eventually forms a single adrenal vein that usually drains into the vena cava on the right and into the renal vein on the left.
Anatomy and Physiology of the Adrenal Glands: Arterial Supply – Imaging