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  • In PET-CT imaging, Standardized Uptake Value (SUV) is used to
    • quantify the metabolic activity of a lesion.
    • The significance of SUV depends on the
      • context,
    • but the following general thresholds are widely accepted for assessing malignancy:
    • SUV < 2.5:
      • More likely to indicate a benign process.
      • However, low-grade malignancies (e.g., some adenocarcinomas, carcinoids, or mucinous tumors) can have low SUVs.
  • SUV > 3-4:
    • Strongly suggests malignancy in many clinical scenarios, particularly in the lung, unless other clinical or imaging findings point to a benign cause.